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Multiple sclerosis symptoms like vision changes, muscle weakness, and balance problems often come and go in "episodes," with 85% of patients initially experiencing relapsing-remitting patterns

A recent study reveals that genetic defects in the NIK/non-canonical NF-B pathway, including autosomal-recessive mutations of NIK or RELB and autosomal-dominant mutation in NFKB2 impairing p100 processing, are associated with production of IFN-neutralizing autoantibodies [60]

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