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Side effects and tolerability Gastrointestinal side effects dominate the retatrutide safety profile

This really comes down to safety and effectiveness

10.1038/nature11048 Nature 35 ChoyM.SalbuR

Despite this, between-group differences were not evident on outcome measures, including the secondary outcome of self-reported PTSD symptoms, which was highly correlated with clinician-assessed PTSD measurements at weeks 0 and 12