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ChemistrySelect 8(48):e202303101 Ali BH et al (2008) Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research

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Altogether, these results indicated that SIRT1 overexpression effectively reduced noise-induced oxidative stress and preserved synaptic and neural integrity in the cochlea

Low oral bioavailability and rapid systemic clearance in rats further complicate its toxicological assessment

To fully understand all these concepts, the most important thing is to know what oxidative stress consists of: it is an imbalance between the production of reactive oxygen species (ROS) and the ability of a biological system to quickly decode the reagents that can cope with them (antioxidants) or to repair the resulting damage