The deficiency worsens with age and is accelerated by chronic illness, medications, and environmental toxins
Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

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Side Effect Profile: advantage goes to Matrixyl
However, their concurrent catalase-like activity undermines therapeutic efficacy by converting hydrogen peroxide in tumor tissues into oxygen, thus diminishing hydroxyl radical production