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In an April post on X, Kennedy wrote that for each peptide, the committee will weigh the full clinical, pharmacological, and safety evidence. The next day, he asserted that these peptides are like supplements, and therefore might not need to go through clinical trials

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Preclinical research has demonstrated cytoprotective properties across multiple organ systems, including the gastrointestinal tract, liver, pancreas, heart, and nervous system

Mechanisms of metformin action: in and out of the gut

They have demonstrated efficacy in alleviating pain associated with diabetic neuropathy, neuralgia, and low back pain, as well as promoting nerve conduction, making them beneficial for a variety of neurological and pain-related conditions