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Veljaa M, Krni , Braja K, Mildner B, Pavi-Sladoljev D, eveljevi-Jaran D et al

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Agents that affect the ferroptosis pathway by modulating the accumulation of iron, ROS, and lipid peroxides Therapeutic strategy focusing on metabolic vulnerabilities and nutrient addiction In response to dynamically changing nutrient availability in the tumor microenvironment, cancer cells facilitate cellular adaptations to reprogram metabolic pathways

Early intervention can prevent progressive worsening of the deformity and may allow for less extensive surgical correction

Also, it was shown that the epigenetic changes (DNA methylation patterns) to be associated with oxidative stress markers 39,40