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(3) Detoxification: Glutathione plays a crucial role in detoxifying the body by neutralizing harmful toxins and free radicals

These metabolites spanned across five key classes: Carbohydrate Metabolomics, Nucleotide and Its Metabolites, Organic Acids and Derivatives, Phosphate Sugars, and Phosphoric Acids, suggesting a metabolic realignment in response to the redox disequilibrium induced by the absence of GR

Other studies confirmed that continuous afferent vagal stimulation reduces inflammatory neuroglia in the SN, upregulates rate-limiting enzyme density in the LC, and alleviates motor deficits in PD rat models (111)

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Approximately 159.21 Da refers to the free positively charged component, while approximately 286.11 g/mol includes the iodide counterion