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The high local concentration is exactly what's needed to study the peptide's direct effects on the damaged intestinal wall

Despite the observed accumulation of AuNPs in the spleen and liver, which did not cause organ damage in these studies, concerns regarding the long-term safety of these NPs were raised

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Moreover, mitochondrial translocase facilitates the progressive accumulation of mitochondrial A in the brains of transgenic mice overexpressing human APP, which correlates with diminished activity of electron transport chain complexes III and IV and a decreased rate of oxygen consumption (43)