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Vitro Toxicol

The solutions described in Table 2 were thus obtained

262 Based on this, knocking down LSD1 can be used as an important target for the treatment of colorectal cancer by attenuating CD133 + cell stemness characteristics (Table 2)

THC directly activates cannabinoid receptors CB1R and CB2R to produce its pharmacological actions, whereas CBD is thought to be an indirect agonist that boosts endogenous concentrations of the endocannabinoids like AEA via inhibition of fatty acid-binding proteins (FABPs) [34], such as FABP5 and FABP7 [35]

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