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Introduction Epilepsy, a complex neurological disorder characterized by recurrent seizures, is a prevalent condition that affects approximately 50 million people worldwide, making it one of the most common neurological diseases and a significant public health issue (GBD 2016 Epilepsy Collaborators, 2019

Conversely, a purified synthetic peptide may achieve a different exposure profile

Are accompanied by severe or unmanageable pain

In addition, the sample size was small (30 patients), which may not be sufficient to draw comprehensive conclusions

Semaglutide GLP-1 pathway Semaglutide is a GLP-1 receptor agonist already FDA-approved for chronic weight management as Wegovy (2.4 mg) and for type 2 diabetes as Ozempic