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Cell Signaling Technology), or rabbit anti-GAPDH (cat# 2118

Clin Pharmacol Toxicol Jour 2017;1:3

Importantly, SIRT1 is directly involved in central clock regulation via modulation of transcriptional activity and stability of Per2 and PGC1-mediated Bmal1 expression (69), and SIRT1 signaling disruption has been associated with sleepwake cycle changes in aging (70, 71)