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Per the applicant, SeptiCyte RAPID is a gene expression assay used in conjunction with clinical assessments and other laboratory findings as an aid to differentiate infection-positive (sepsis) from infection-negative systemic inflammatory response syndrome (SIRS) in patients suspected of sepsis on their first day of intensive care unit (ICU) admission

this was consistent with the general pattern based on enzymatic digestion and MS fragmentation methods

This dependence on host metabolites most likely requires massive reprogramming of the host cell metabolism upon infection by this pathogen

PMID: 19 ZhuZWangYDengZLeiPLiuQGuoJet al

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