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In viral sepsis, HIF-1 accumulation mainly depends on the combined action of viral proteins (e.g., C16 of VACV or LMP1 of Epstein-Barr virus) on PHD activity regulation, PRR-mediated innate immune responses, and local hypoxia in lung tissue (7981)

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One approach to decreasing technical errors for emergency general surgery procedures in the era of increased specialization is the development of an "acute care surgery" specialty