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Restoring the GH/IGF-1 axis through this GHRH analog produces several secondary benefits that are clinically meaningful for patients with metabolic syndrome: Lean mass preservation

BBB-on-a-chip system replicates central nervous system barriers to test drug delivery to brain tumors and evaluate parameters such as homeostasis and permeability

For glioblastoma (GBM), a blood-brain barrier-penetrating delivery system was developed using Angiopep-2/TAT peptide-modified extracellular vesicles (EVs) to transport Cas9/sgRNA complexes targeting glutathione synthetase (GSS)

Further analysis of rat in vivo CL u and in vivo V ssu revealed that the observed improvement in half-life, in cases where it was statistically significant, was achieved despite the increase seen in in vivo CL u (Table S1 and Figure S3)