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Summary Keywords bioavailability, ellagic acid, ellagitannins, pharmacokinetics, polyphenols, punicalagin, TMA Citation Haarhuis JE, Ahn-Jarvis J, Savva GM, Day-Walsh PE, Ferns C, Hughes S, Triller S, Al-Jaibaji O, Philo M, Acaroz E, Perez-Moral N and Kroon PA (2026) Effect of a polyphenol-rich pomegranate extract on plasma trimethylamine N-oxide levels following an oral carnitine challenge: a randomized controlled crossover trial in healthy adults

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Anxiety disorders are documented and categorized in diagnostic systems such as the American Psychiatric Associations Diagnostic and Statistical Manual of Mental Disorders (DSM, now version IV-TR) or the International Classification of Diseases (ICD) (ICD, current version 10, World Health Organization) (19)