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Description

Since COX-2 was found to be underexpressed, inadequate COX-2 regulation may also be involved in the pathogenesis of AEA

Innate Immun

Oikari S, Makkonen K, Deen AJ, Tyni I, Karna R, Tammi RH, et al

6:e12078

Activated T cells express FasL, which binds to FasR on the target cell surface, recruiting FADD to the cytoplasmic side and activating caspase 8, thereby initiating the apoptosis cascade and triggering cell death