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Following absorption from the Gastrointestinal tract, paracetamol is metabolised predominantly in the liver where it is conjugated into inactive glucuronide and sulphate conjugates, which are excreted in urine, and toxic N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione

Chlorogenic acid and luteolin synergistically inhibit the proliferation of interleukin-1beta-induced fibroblast-like synoviocytes through regulating the activation of NF-B and JAK/STAT-signaling pathways

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Barlow, J