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Patients were randomly assigned 1:1:1 to one of three treatment groups (5, 20, and 80 mg TID)

5 Pathophysiology of DN DN is a multifaceted neurodegenerative disorder resulting from the interplay of metabolic, vascular, and neurodegenerative processes primarily driven by chronic hyperglycemia

Stay at the new dose for another week before increasing it again

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Combined support strategies include: Integrated treatment planning Multi-specialist coordination Regular progress assessment Flexible intervention methods Family education programs School-home communication systems Why Understanding the Difference Matters Tailoring Interventions Understanding differences between conditions leads to more effective support