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126 In an open-label controlled trial in healthy middle-aged adults, 900 mg of cocoa flavanols per day for 30 days improved endothelial function, an important factor in thrombotic risk, and in a follow-up controlled trial the same dose was also shown to improve blood pressure and lipid levels

Heilig R, Broz P (2018) Function and mechanism of the pyrin inflammasome

Anti-amyloid mAbs have shown the greatest improvements in AD outcomes to date, reduce plaque burden, and are the first disease-modifying treatments shown to slow disease progression and cognitive decline (Gregory, 2023)

Despite promising advances, challenges remain

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