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Etheresia Pretorius, orcid.org/0000-0002-9108-2384 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This trial was the first to evaluate the use of oral N-acetylcysteine in monotherapy, associated with broad-spectrum sunscreen, for the treatment of melasma

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[3] It could have efficacy in preventing the development of nitrate tolerance