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C.SundaramC.ReuterS.AggarwalB

Gastric mucosa performs limited first-pass metabolism before ethanol reaches portal circulation, reducing bioavailability slightly before systemic distribution begins

Several clarifications are important for interpreting this table

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In this review, we summarize the current knowledge on the role of bile acids and the receptors in the development of NAFLD and NASH, especially the functions of farnesoid X receptor (FXR) in different tissues including liver and intestine