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Furthermore, the competitive, independent, or sequential binding of Pin1 and Lck to PKC may differ among T cell subtypes and thereby explain the differential recruitment of PKC to the IS of Th/Tc vs its recruitment to the opposite cell pole in Treg

Both authors read and approved the final manuscript

Besides, the pro-inflammatory response can be shifted to anti-inflammation by H 2 S donors, as demonstrated to decrease the levels of TNF-, IL-8 and IFN-, while increasing the levels of cyclooxygenase (COX)-2 and eicosanoids 90

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Notably, the HG-3 cells had a relatively high basal level of autophagy