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337,338 Structural mitochondrial abnormalities such as disrupted cristae are widely documented in FTLD-TDP, AD, mixed AD/PD, and HD, linking altered mitochondrial architecture to impaired ATP production, calcium dysregulation, synaptic dysfunction, and eventual neuronal death

Although lower Fe 2+ concentration and extended culture time resulted in a higher Fe 2+ removal rate (Supplementary Fig

2) elucidating the dynamics of how protein machinery is captured and retrofitted for viral purposes in a cell-specific manner

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