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PMID: 11313273

PloS one 12 , e0176883 (2017)

Lin Y, Shi R, Wang X, Shen HM

How Ibuprofen Affects Glutathione Research has indicated that certain NSAIDs, including ibuprofen, may have an effect on glutathione levels in the body

Pt-induced ROS production easily breaks the balance of endogenous ROS and cellular antioxidant systems to trigger oxidative stress and mitochondrial dysfunction, resulting in the damage or loss of DRG cells containing abundant ROS-sensitive phospholipids (Khasabova et al., 2019)