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Transient tear hyperosmolarity disrupts the neuroimmune homeostasis of the ocular surface and facilitates dry eye onset

Micro-infusion and microneedling-inspired tools are used cosmetically to create temporary microchannels in the upper skin surface, helping the serum spread more evenly across the targeted area

BT474 cells and PC3- hTERT cells were cultured in DMEM F-12 medium (Gibco, Invitrogen) with 10% FBS (Gibco, Invitrogen) and 1% PenicillinStreptomycin (Gibco)

doi: 10.1016/j.ecoenv.2020.111887 22

10.3390/ijms13044831 9 BeauregardA.-P.HarquailJ.Lassalle-ClauxG.BelbraouetM.Jean-FrancoisJ.TouaibiaM.et al (2015)