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Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease

Dietary fibers could be fermented by some species of gut microbiota and produce SCFAs, which provide energy to intestinal epithelium cells and strengthen the intestinal barrier, preventing inflammation induced by LPS (Seethaler et al., 2022)

Exclusion criteria in both groups were as follows: secondary causes of small intestine and/or colonic disease, systemic diseases, any malformations, evidence of intestinal bacterial or other infection, history or evidence of any inherited metabolic disease, hepatic or renal disease, and pregnancy

Copper peptide cream 70% response rate, vitamin C 50%, tretinoin (retinoic acid) 40%