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& Okada, Y

Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis

To obtain the best possible outcome, NAC should be administered as soon as possible where impending or evolving liver injury is suspected

Free iron can be used in the Fenton reaction with H 2 O 2 to generate OH consequently contributing to further enhancement of oxidative stress, lipid peroxidation events, and ovarian damage [21, 59]

Thus, future research should explore the potential of metformin in preventing IIRI in patients with early risk factors, and develop combinatory treatments that offer both immediate and sustained protection against IIRI