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The carbon-based sorbents provide good removal of carotenoids, chlorophyll, and sterols, whereas addition of octadecyl silica (C18) is recommended for samples rich in fat and waxes (Rejczak and Tuzimski 2015)

Notably, prophylactic administration of curcumin prior to A deposition demonstrates preventive potential for AD, possibly through facilitating A 42 clearance from the brain to peripheral circulation ( The therapeutic efficacy of curcumin in AD is considerably constrained by its limited ability to cross the blood-brain barrier

Superoxide dismutases (SOD), catalase (CAT), and peroxidases using, e.g., Asc (ascorbate peroxidase, APX), GSH (glutathione peroxidase, GPX), or phenolic compounds as electron donors for peroxides reduction, are examples of ROS-detoxifying enzymes (Gechev et al

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Both oxidative stress and mitochondrial damage are associated with reduced levels of renal sirtuin 3 (SIRT3)