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In addition, alkylating cytostatics are distinguished by pharmacokinetics, lipid solubility, and exact chemical reactivity, which is caused by different functional groups independent of carcinogenicity

It can be speculated that, in a condition of high aggressiveness, typical of GBM, an increase of carnitine cell content is required to sustain the high energy demand of cell proliferation

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Cette diminution peut tre accentue par un excs dactivit physique mais aussi par certaines maladies, de mme que par une exposition accrue aux toxines, la prise de mdicaments, la pollution environnementale etc

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