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HS exhibits a biphasic effect in cancer biology: at low concentrations, it enhances mitochondrial function and promotes glycolysis, thereby supporting cancer cell proliferation, whereas at high concentrations, it inhibits proliferation

Breisch et al., 2022)

Because metabolite-receptor interactions are often highly stereospecific 53,54 , we developed a synthesis employing Sharpless chiral resolution and subsequent chirality transfer via Claisen rearrangement to access the two enantiomers of bemeth#1, (3 R) -bemeth#1 and (3 S) -bemeth#1 (Fig

Energy Conversion: Supports mitochondrial ATP production and cellular metabolism [Rebouche 2004]

Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria: identification, purification, characterization, and induction by peroxisome proliferators