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Metabolism of branched-chain amino acids in fibroblasts from patients with maple syrup urine disease and other abnormalities of branched-chain ketoacid dehydrogenase activity

When (R)-4-chloro-3-hydroxy butyric acid alkyl ester was prepared by the hydrolysis of racemic 4-chloro- 3 -hydroxy butyric acid alkyl ester in an aqueous solution or an aqueous solution-containing solvent using immobilized lipase, the reaction product was extracted with ethyl acetate and analyzed by gas chromatography (Model No

Burden of disease in the belt and road countries from 1990 to 2021: analysis of estimates from the global burden of disease 2021

From there, it's no surprise that the EC3 spread like wildfire