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10.1126/science.aau6977 30 LeeJ.RohJ.-L

By reducing the accumulation of these toxic aldehydes, ALDH2 contributes to mitigating oxidative stress (49)

The minimum stock levels of antidotes vary according to the level of hospital, ranging from two patients at primary centers to more than 10, including specific antidotes, at super tertiary centers

In diabetic nephropathy, kidney dysfunction accompanied by nephron loss has been attributed to inflammation, ECM accumulation, and tubular cell death, which is also seen in nephrotoxic and ischemia-reperfusion injury models 27,28