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NLRP3, the most widely studied inflammasome, is a high molecular mass protein complex composed of NLRP3 protein, Apoptosis-associated Speck-like protein Containing a CARD (ASC), and cysteine aspartate protease 1 (caspase-1)

Adipocyte size analysis was performed using the Keyence BZ-X Analyzer software based on brightfield images of H&E-stained paraffin sections

With topical corticosteroids as the primary treatment, ACD is currently a pathology without a permanent cure

Helps convert melanin from the darker eumelanin to the lighter pheomelanin, reducing skin pigmentation

Hematoxylin and eosin staining were performed for 5 min each on the sections