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Autophagy is induced by various stress conditions, such as nutrient starvation, hypoxia, and microbial infection (153)

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They assessed the impact of five distinct optical and nuclear tracers on the biodistribution of EVs in vivo, including lipid fluorescent dye DiR, the radioisotope 111 indium-DTPA, and either fluorescent proteins fused to the EV marker CD63 (mCherry) or bioluminescent proteins (firefly and NanoLuc luciferase) to label Expi293F EVs