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In addition, it has also been shown that the NRF 2 /ferroportin 1 (FPN 1 ) signaling pathway is a key mechanism in diabetic myocardial injury, inhibiting ferroptosis by regulating iron metabolic homeostasis, and its activation alleviates diabetic myocardial injury to some extent (64)

Additionally, metformin has been shown to upregulate the expression of GLUT4 in endometrial cells of patients with PCOS, thereby inhibiting the progression of EC (Li et al., 2023)

To visualize proportions of women included in studies over time, scatterplots over time were plotted weighted by study sample size

Symptoms typically appear 1-3 days after bacterial introduction and include dysuria (burning urination), urgency with minimal output, and cloudy urine with a strong odor