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The specific molecular mechanism involved TSA maintaining Nrf2/ARE pathway activity by inhibiting 6-OHDA-induced upregulation of miR-153, which targets the 3'-untranslated region of Nrf2, thereby exerting neuroprotective effects (73)

Originally from Greeley, Colorado, Meline earned a Master of Public Health degree from Johns Hopkins University and a Bachelor of Science degree in Chemical Engineering from the University of Colorado, Boulder.