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5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology

Research showed that cellular damage, such as ferroptosis and pyroptosis, might intensify the process of tau hyperphosphorylation and an inflammatory response linked to AD progression (Qiu et al., 3 Mechanisms of ferroptosis Ferroptosis is characterized by unchecked peroxidation of lipids and consequent disruption to the cellular membrane, its onset and development are controlled by intricate signaling and regulatory mechanisms

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In this review, we outline the pathogenesis of ferroptosis, regulatory mechanisms of ferroptosis, related regulatory molecules, and their effects on epilepsy, providing a new direction for discovering new therapeutic targets in epilepsy