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Exosome engineering using genetic and chemical methods for targeted drug delivery boasts low toxicity, low immunogenicity, and high engineerability, which holds promise for cell-free therapies [74]

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Instead, are enlisted 30 clinical studies involving the administration of polyphenols in various types of cancer and 50 clinical studies using polyphenols to counteract oxidative stress (Table 2 and Table 3, respectively)

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