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In addition, 16S rRNA gene sequencing and genomic identification could achieve the comprehensive analysis of bacterial flora in tumor-bearing animals, which would be another method to evaluate the effects of the dual-functional therapies (Zeng et al., 2025)

As a novel therapeutic approach, host-directed therapy (HDT) has gained attention as an avenue for improving treatment outcomes of drug-resistant TB and is being increasingly explored as an adjunct TB treatment [3]