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1 Introduction Diabetes has become a global public health crisis, with epidemiological data revealing a prevalence of 10.5% among individuals aged 2070 years, projected to climb to 12.2% by 2045 (Sun et al., 2021)

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When B12 levels are optimised, mitochondriayour cells' power plantscan function more efficiently, resulting in sustainable energy throughout the day

153 While in-vitro models can assess these physiological parameters, achieving precise reproducibility in in-vivo settings for evaluating side effects remains a formidable challenge