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PV1-BSOr mutants evolved rapidly, already during the first passages on BSO-treated HeLa cells

Characteristics and concordance of autism spectrum disorders among 277 twin pairs

This instability may result from inadequate demethylation of conserved non-coding sequence regions in the Foxp3 locus, known as the Treg-specific demethylation region (TSDR), which is fully demethylated in thymus-derived Tregs (tTregs) but often methylated in iTregs (38)