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Elevation of intracellular Ca 2+ activates scramblase to ensure PS externalization, opens the Gardos channels, resulting in K + efflux and subsequent cell shrinkage, and mobilizes calpain, leading to cytoskeleton degradation and membrane microvesiculation [78]

NOTE ADDED IN PROOF After this article was submitted for publication on January 2, 2013, the following article was published prior to publication which strongly supports the hypothesis in the current article

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Processed and ultra-processed foods are associated with depression and anxiety symptoms in a cross-sectional sample of urban Lebanese adults

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