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DMT1 inhibitors kill cancer stem cells by blocking lysosomal iron translocation

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Studies have found that berberine attenuates ischemia-reperfusion injury through NF-B nuclear translocation in mice with transient cerebral artery occlusion, however, this neuroprotective effect was more pronounced at the high dose (50 mg/kg) than the low dose (25 mg/kg) (Zhu et al., 2018)

doi: 10.1016/j.abb.2010.04.018

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