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Indeed, as evidenced by the pioneer works of Grace and collaborators, an increased ventral hippocampal activity causes the nucleus accumbens to strongly inhibit the ventral pallidum, which in turn increases the number of spontaneously active ventral-tegmental-area dopamine neurons [151, 154]

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The salivary levels of OS markers, including thiobarbituric acid reacting substances, advanced oxidation protein products, and advanced glycation end products (AGEs), in patients with severe OSA were higher in the morning compared to the past evening