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In the PINK1/Parkin pathway, PINK1 accumulates on the outer mitochondrial membrane when the membrane potential is lost, leading to the recruitment of the E3 ubiquitin ligase Parkin

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Effective natural remedies include increased hydration, magnesium and potassium supplementation, moist heat therapy, stretching and yoga, massage therapy, acupuncture, and stress-reduction practices like progressive muscle relaxation and diaphragmatic breathing

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