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However, the lack of drug-like characteristics, such as poor target specificity and selectivity, high toxicity, several off-targets, severe side effects, poor metabolic stability, poor membrane permeability and rapid proteolysis, make this molecule fairly unsuitable candidates for therapeutic applications

Hydrolysed collagen is easier to digest, which makes it better for support of skin and connective tissues

AAV-Cre-GFP-injected mice exhibited less freezing behavior compared to controls during the acquisition phase, but they displayed normal fear memory 24 h after conditioning (Fig

Moreover, the pCTV vector showed similar expression levels, when compared to pCDNA (Fig

But adjunct therapy on top of a sub-optimal foundation is unlikely to produce the result the patient is looking for, and can produce confusion about what is and is not working