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Previously, Christopher's group disclosed 2-amino-3,5-diarylbenzamide inhibitors ( Figure 20 ), and found the advantage of the sulfonamide moiety for the IKK inhibitory potency [188]

Stabilizing GSH during storage and post-sterilization, maintaining antioxidant functionality throughout processing, and scaling fabrication methods for multilayered or 4D-printed constructs remain key challenges to regulatory advancement [44]

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Both the viral S protein component (i.e., mRNA, protein, or peptides) as well as adjuvants such as polyethylene glycol (PEG) are capable of eliciting antibody response in B cells, resulting in antigen- and/or PEG-specific IgE and IgG antibodies (Figure 2)

Although those studies are still ongoing