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doi: 10.1111/j.1462-5822.2007.00902.x [DOI] [PubMed] [Google Scholar] 273.Pereira CF

One route is the reductive amination of 2-oxoglutarate with ammonium as the nitrogen donor via glutamate dehydrogenase (GDH) (Fig

Of particular interest, immunosuppressive TAMs derived from M-MDSCs persistently express S100A9, a protein that sustains their T cellsuppressive activity and is associated with poor response to immunotherapy in multiple cancers [133]