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These may include: Temporary soreness, redness, or swelling at the injection site Mild flushing (particularly due to niacin, or vitamin B3) Occasional lightheadedness or mild nausea, which typically passes quickly Adverse reactions are uncommon, especially when administered by trained medical professionals

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[39] [40] Pharmacology [edit] Pharmacokinetics [edit] A 2007 human pharmacokinetic study of sodium RLA demonstrated the maximum concentration in plasma and bioavailability are significantly greater than the free acid form, and rivals plasma levels achieved by intravenous administration of the free acid form

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However, translating these discoveries into clinically validated tools requires overcoming challenges related to inter-individual variability, standardization, and the establishment of causality