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We reveal that OsBAK1 interacts with and phosphorylates OsSRF3 to activate PTI responses, whereas UgsL promotes OsSRF3 degradation through the ubiquitin-26S proteasome, thereby inhibiting OsBAK1OsSRF3-mediated immune pathways

Provided that astrocytes are the main steroidogenic cells in the brain ( In addition, TLR signaling may play a neuroprotective role in EAE and by extension, in MS, although this effect might not be astrocyte-specific